What is PDRN (Polydeoxyribonucleotide), How does it work for skincare, and why is it getting so popular?

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Customer: Cheryl R.
Skin Type: Dry
Skin Concern: Hyperpigmentation, wrinkles & fine lines, Hyperpigmentation
Skin Stage: Mature (age 55 to 64)

Question From Cheryl

MHi Saranghae,

I stumbled across your podcasts and really enjoyed them. They are informative but also quite funny.

There was one post that touched on a new ingredient called PDRN and it’s something that’s been coming up within my circle of friends as well but no one seems to know exactly what it is.

 Can you explain PDRN? What is it, how does it work and why is it getting so popular right now?

Thanks Cheryl

Saranghae Recommendation

Hi Cheryl,

Thank you for your kind words and I’m happy you enjoy our podcasts. It’s an interesting way to discuss ideas without getting too academic and Andrea and I have a lot of fun recording them.

Now let’s talk about PDRN.

PDRN has been percolating in K-beauty for about 10 years now, mostly in medical circles but it’s become the focus ingredient in the last year.  We noticed a definite increase in buzz during our last trip to Hong Kong.

PDRN is an acronym for Polydeoxyribonucleotide and if that sounds familiar that’s because it’s very close to DNA (deoxyribonucleic acid), the blueprint of any living organism. PDRN is a subset of DNA and in the current case, it is extracted from salmon sperm or synthesized in labs.

Why salmon sperm? It’s due to bioavailability, or how similar the DNA is to human DNA. Aside from human sperm, PDRN from salmon sperm seems to match the closest to humans making it highly bioavailable.

By the way, that is also why we offer marine/fish collagen in our collagen supplement.

In a growing body of research, PDRN shows excellent cell regenerative and healing properties by stimulating the production of growth factors within our body which leads to better and faster skin regeneration. It also helps reduce inflammation by modulating our immune response making it beneficial for all kinds of skin conditions such as acne, rosacea, or eczema.

There is even talk that it can help repair damaged DNA which can lead to various remedies that help with long-term sickness, perhaps even cancer.

How valid is all of this hype?

We’re not quite sure yet. We’ve seen so many skincare fads come and go and the pattern here is no different. The science does look promising and the number of research papers is starting to build. But the studies are too recent and we need more research with different use cases.

However, we do think it’s far enough along where we want to start exploring if it fits our brand.  So we are we are currently looking into developing a serum based on PDRN.  How long that will take to bring to market? We’re not sure, but it’ll be at least a year if not more.

I hope this helps answer at least some of your questions.

Please don’t hesitate to contact us at customercare@lovesaranghae.com should you have any more questions

My warmest regards
Peter Lee
Co-founder, CEO
Saranghae | Orora

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